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Bugs and drugs: A work in progress

Gut microbes possibly influence not only the development of many human diseases, but also how these diseases respond to treatment. In tumor models, for example, gut microbes can modulate the efficacy and toxicity of...

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Developing an HIV vaccine

In 2015, 17 million HIV-infected individuals worldwide were on antiretroviral drug therapies, which are remarkably effective in suppressing the virus. Yet, 6000 people a day became newly infected, making the quest for an effective...

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Preliminary Clinical Trial Demonstrates Feasibility of Treating Multiple Myeloma with the Patient’s Own Marrow-Infiltrating Lymphocytes

Results of a small clinical trial support the feasibility of using a multiple myeloma patient’s marrow-infiltrating lymphocytes (MILs) as the basis for adoptive T cell therapy (ACT). Investigators at Johns Hopkins University (Baltimore, MD,...

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