Tagged: stem cells

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Blood Stem Cells Grown in the Lab

Two teams of scientists have generated blood stem cells by reprogramming either human or mouse cells. In both cases, these hematopoietic stem cells successfully produced blood cells when implanted into mice. “This is important...

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Donor Stem Cells Improve Cardiac Function

Cardiac muscle cells derived from induced pluripotent stem cells (iPSCs) and injected into monkeys helped the animals’ hearts recover from a heart attack, according to a study published yesterday (October 10) inNature. The iPSCs...

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Zika Infects Adult Neural Progenitors Too

Zika virus exposure in a mouse model can infect adult neural stem cells in the brain, leading to cell death and reduced proliferation.CELL STEM CELL, H. LI ET AL.Microcephaly and associated birth defects in...

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CRISPRi-Controlled Gene Expression

A team of researchers at the Gladstone Institutes in San Francisco, California, has used a version of CRISPR gene editing known as CRISPR interference (CRISPRi) to reversibly and accurately suppress gene expression in induced pluripotent...

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CRISPR Corrects Retinal Disease Mutation

Retinitis pigmentosa, an inherited disease causing progressive degeneration of the retina, is repsonsible for blindness in approximately 1.5 million people worldwide. Using patient-derived stem cells, researchers in the U.S. have now used the CRISPR/Cas9...

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STEM CELLS AND HEALTHY AGING

Research into stem cells and aging aims to understand how stem cells maintain tissue health, what mechanisms ultimately lead to decline in stem cell function with age, and how the regenerative capacity of somatic...

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Cancer: Repositioned to kill stem cells

Chemotherapy-resistant cancer stem cells make it hard to cure many forms of the disease. Repositioning an existing drug to tackle this problem could significantly improve treatment for one form of leukaemia….

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Mitochondria Swap

Scientists have used two methods to generate patient-specific pluripotent stem cells with normal mitochondria for people with defects in these organelles, according to a study published today (July 15) in Nature. The first method...

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Graphene Demonstrates Anticancer Activity

Scientists at the University of Manchester say they have used graphene to target and neutralize cancer stem cells while not harming other cells. This new development opens up the possibility of preventing or treating a...

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Stem Cells Phone Home

Pretreating human mesenchymal stem cells (MSCs) with a small molecule called Ro-31-8425, researchers can increase the expression of the surface receptor CD11a to improve the cells’ ability to target to inflamed tissue, according to...

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