Tagged: Parkinson’s disease

Deep Brain Stimulation Without Surgery

Deep brain stimulation can improve debilitating, treatment-resistant brain disorders but involves surgically implanting electrodes that often have to penetrate multiple layers of tissue before reaching their targets. In a mouse study published today (June...

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Parkinson disease

Parkinson disease is the second-most common neurodegenerative disorder that affects 2–3% of the population ≥65 years of age. Neuronal loss in the substantia nigra, which causes striatal dopamine deficiency, and intracellular inclusions containing aggregates...

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α-Synuclein’s sufficient

α-Synuclein (α-syn) may promote Parkinson’s disease–like pathology by cell-to-cell transmission in mice, according to a new report in Science (338, 949–953, 2012). Parkinson’s disease is characterized by abundant α-synuclein (α-Syn) neuronal inclusions, known as Lewy bodies and Lewy...

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