Tagged: neuroscience

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Talking sensibly about depression

Summary points Depression is the leading mental health—related cause of the global burden of disease and is the focus of World Health Day 2017. Despite robust evidence of the effectiveness of interventions ranging from...

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Why pain and stress lead to depression

Chronic stress or pain is associated with the development of depression. Descalzi et al. examined gene expression changes in the brain in mouse models of nerve injury– or chronic stress–induced depression. They found some...

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How Experience Shapes Adult Neurogenesis

Newly made cells in the brains of mice adopt a more complex morphology and connectivity when the animals encounter an unusual environment than if their experiences are run-of-the-mill. Researchers have now figured out just...

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Nascent Neurons Journey Through Newborn Brain

The human cerebral cortex experiences a burst of growth late in fetal development thanks to the expansion and migration of progenitor cells that ultimately form excitatory neurons. For a fully functional brain, in addition...

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Encoding false memories

A unique human ability is the use of concepts that confer meaning in an abstract way. Despite the importance of conceptual knowledge for human cognition, scientists know little about the underlying neural mechanisms and...

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Environmental Magnetite in the Human Brain

In more than three dozen postmortem human brains, scientists have detected nanoparticles of magnetite that they suspect came from the environment. The brain produces magnetite particles that are associated with Alzheimer’s disease, but these...

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How Blasts Affect the Brain

Explosions during military combat can initially cause mild traumatic brain injury (TBI), which may lead to later development of neurodegenerative disorders like chronic traumatic encephalopathy and Alzheimer’s disease. What happens when the brain is...

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Top Technical Advances 2015

Imaging Life-science imaging broke barriers this year, as scientists built upon microscopy approaches to peer ever deeper into living tissues. In October, Purdue University’s Ji-Xin Cheng and colleagues reported they had greatly increased the...

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More neurons mean less need for sleep

Sleep is seemingly universal among animals. Daily sleep time varies considerably between mammalian species and also during mammalian development, yet we still don’t know what drives this variation. Herculano-Houzel hypothesized that sleep-inducing metabolites produced...

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