Tagged: microbiome

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Immune sensor maintains gut microbiome

Emerging evidence indicates that the immune system can influence microbiome composition. Chen et al. now report that patients with active ulcerative colitis have low expression of NLRP12, which is best known for its role...

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Viruses of the Human Body

S ince the dawn of microbiology, researchers have focused on pathogens that make us and our domesticated animals and plants sick. Because the onset of symptoms was the only way to know if specific...

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Can a Dirty Mouth Worsen Colorectal Cancer?

Evidence emerges almost daily in support of the microbiome’s influence on a variety of body systems and disease states. Yet, can it be true that various microbes that constitute the oral microbiota negatively affect...

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Fecal Transplant Pill Fails Trial

Earlier this year, Seres Therapeutics publishedpromising data from an early-stage trial for its SER-109, a pill containing bacterial spores isolated from stool samples for patients with recurring Clostridium difficile infections (CDIs). The therapy seemed to be...

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Spoiler Alert

n the last decade or so, researchers have spent billions of dollars categorizing the microbes that populate sites as disparate as the human body, soil, and the oceans. Much of what we know about...

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Metformin Users Have Different Gut Bugs

Diabetics who use the commonly prescribed drug metformin to control blood sugar levels have a different composition of gut microbiota than other diabetics, according to a study published in Naturelast week (December 2). The...

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Birth of the Skin Microbiome

The skin is home to millions of commensal bacteria and immune cells. Yet how the skin microbiome is established in particular, why the immune system does not attack these bacteria—has been little studied. Now,...

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Bile Benefits

For obese patients undergoing a gastric bypass, such as the commonly used Roux-en-Y procedure, the surgery is extensive. “It basically changes the whole anatomy of the GI tract,” says Naji Abumrad of Vanderbilt University....

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How Fats Influence the Microbiome

The types of lipids mice consume affect the composition of their gut microbiota, which influences whether the animals develop obesity-related inflammation, according to a study published today (August 27) in Cell Metabolism. Mice fed...

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