Tagged: drug research

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Easier cure for resistant TB

A new treatment strategy has had astonishing success against extensively drug-resistant tuberculosis (XDR TB), which kills more than 70% of patients. XDR and other drug-resistant forms of TB are burgeoning among people with HIV,...

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How Much Longer Will We Put Up With $100,000 Cancer Drugs?

The spiraling cost of new drugs mandates a fundamentally different approach to keep lifesaving therapies affordable for cancer patients. We call here for the formation of new relationships between academic drug discovery centers and commercial...

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Could a Diabetes Drug Cure CML?

Chronic myelogenous leukemia (CML) is caused by chromosomal translocation that creates a fused gene; this gene produces an oncoprotein, BCR-ABL. Targeting this protein with imatinib (Gleevec) and other tyrosine kinase inhibitors (TKIs) produces dramatic...

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New drug target for Alzheimer’s?

Mouse models do not fully capture the degeneration of brain networks seen in human Alzheimer’s disease (AD). Thus, extensive validation of therapeutic targets in many animal models must precede human clinical research. Huang et...

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Triple threat

Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide threat to human health, because it is resistant to a large class of β-lactams (penicillins) and to second-generation penicillins, including methicillin. However, Gonzales et al. report that...

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Riboswitch Flip Kills Bacteria

Researchers at the pharmaceutical company Merck have identified a new bacteria-killing compound with an unusual target—an RNA regulatory structure called a riboswitch. The team used its drug, described in Nature today (September 30), to...

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FDA Approves 3-D–Printed Drug

At first glance, SPRITAM looks like any other pill. But the drug, developed by pharmaceutical company Aprecia, is actually layers of powder laid down by a 3-D printer. Its approval this week (August 3)...

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