Tagged: clinical trials

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Rethinking a Cancer Drug Target

A protein thought to be essential for cancer cells may not be so essential after all, according to a study published today (March 24) in eLife. Researchers at Cold Spring Harbor Laboratory (CSHL) in...

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CRISPR Therapy to Enter Trials

Oncologist You Lu of Sichuan University’s West China Hospital in Chengdu and colleagues will soon begin trialing a new CRISPR-based immunotherapy in 10 patients with non-small cell lung cancer that has metastasized and is...

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Tumor Models Bridge Mouse-Human Gap

Precision medicine is all about the two T’s—targets and treatments—targets that emerge from analyses of patient-specific information, and treatments that hit these targets. Both T’s, however, pose difficulties. All too often, insights and drug...

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Clinical Matchmaker

In late 2011, the outlook for AstraZeneca’s cancer drug Lynparza (olaparib) was grim. After an interim analysis revealed disappointing results in a Phase 2 trial, the company ceased development of the ovarian cancer drug....

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Diagnosing Sepsis

A set of 11 genes may be key to distinguishing patients with sepsis, systemic inflammation caused by infection, from patients suffering from inflammation caused by noninfectious sources, according to a study published this week...

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