Tagged: Brain

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Roadmaps for building the neonatal brain

In the postnatal mammalian brain, neurons continue to be generated and migrate to their home stations. Often, these neuroblasts travel along pathways defined by the blood vessels or the glial cells that surround and...

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Relief for retinal neurons under pressure

Advancing age predisposes us to a number of neurodegenerative diseases, yet the underlying mechanisms are poorly understood. With some 70 million individuals affected, glaucoma is the world’s leading cause of irreversible blindness. Glaucoma is...

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Nascent Neurons Journey Through Newborn Brain

The human cerebral cortex experiences a burst of growth late in fetal development thanks to the expansion and migration of progenitor cells that ultimately form excitatory neurons. For a fully functional brain, in addition...

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Encoding false memories

A unique human ability is the use of concepts that confer meaning in an abstract way. Despite the importance of conceptual knowledge for human cognition, scientists know little about the underlying neural mechanisms and...

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Environmental Magnetite in the Human Brain

In more than three dozen postmortem human brains, scientists have detected nanoparticles of magnetite that they suspect came from the environment. The brain produces magnetite particles that are associated with Alzheimer’s disease, but these...

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More neurons mean less need for sleep

Sleep is seemingly universal among animals. Daily sleep time varies considerably between mammalian species and also during mammalian development, yet we still don’t know what drives this variation. Herculano-Houzel hypothesized that sleep-inducing metabolites produced...

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Brain development hamstrung

Mutations in a zinc-finger transcription factor known as Zic2 cause problems in cortical development and can result in schizophrenia symptoms. Studying embryonic mice, Murillo et al. show that this protein supports migrations of several...

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The Brain on Fear

Animals respond to fear in predictable ways. A mouse confronted with danger is likely to either freeze in place or run for its life. But how this primal response is elicited in the brain...

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Modifying Memories During Sleep

Mice can recall artificial memories created during sleep once they’re awake, researchers from the French National Center for Scientific Research (CNRS) and their colleagues reported today (March 9) in Nature Neuroscience. The findings support...

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