Tagged: Bacteria

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Immune sensor maintains gut microbiome

Emerging evidence indicates that the immune system can influence microbiome composition. Chen et al. now report that patients with active ulcerative colitis have low expression of NLRP12, which is best known for its role...

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Why tolerance invites resistance

Bacteria use two strategies to avoid being killed by antibiotics: resistance and tolerance. Resistance mechanisms such as destruction of a drug or modification of its target allow bacteria to grow in the presence of...

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A bacterial global regulator forms a prion

Prions enter another domain of life Prions are self-propagating protein aggregates, discovered in connection with the fatal transmissible spongiform encephalopathies in mammals. Prions have also been identified in fungi, where they act as protein-based...

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New CRISPR-Cas Enzymes Discovered

Microbes use a number of CRISPR-Cas systems for immunity, but it’s the class 2 system, typically utilizing the nuclease Cas9, that has been adapted for genome editing. A metagenomics search of microbes sampled from...

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Superbug Gene Found on Pig Farm

Modern agriculture relies on antibiotics to shield livestock from disease, but widespread over-use of antibiotics has raised concerns over creating highly resistant “superbugs.” Researchers announced this week (December 5) that bacteria carrying a rare,...

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Metformin Users Have Different Gut Bugs

Diabetics who use the commonly prescribed drug metformin to control blood sugar levels have a different composition of gut microbiota than other diabetics, according to a study published in Naturelast week (December 2). The...

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Birth of the Skin Microbiome

The skin is home to millions of commensal bacteria and immune cells. Yet how the skin microbiome is established in particular, why the immune system does not attack these bacteria—has been little studied. Now,...

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Skin Microbes Help Clear Infection

To understand whether the human skin microbiome can affect the ability of a bacterial pathogen to cause an infection, researchers have had to rely on observational studies. Now, taking advantage of a unique human skin...

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Sealed With a Kiss

Locking lips spreads more than just love. A healthy dose of microbes are also swapped between kissing couples, according to a study published today (November 17) in Microbe. Researchers in Amsterdam swabbed the mouths...

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Bacteria help norovius infect B cells

Stomach ache, nausea, diarrhea—many people know the sort of gastrointestinal havoc norovirus can wreak. Despite this, norovirus biology remains unclear, because human norovirus cannot be grown in culture. Jones et al.now report that with...

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