Putting Glioblastoma in Its Place: IRF3 Inhibits Invasion

Siobhan S. Pattwell, Eric C. Holland

With an unsurpassed capacity for invasion into normal brain tissue, glioblastoma multiforme is the most lethal primary brain tumor. New research suggests that altering a subset of extracellular matrix factors, including interferon regulatory factor (IRF)3 and casein kinase (CK)2, may decrease the migratory potential of these aggressive tumors.

Leave a Reply