Putting Glioblastoma in Its Place: IRF3 Inhibits Invasion

Siobhan S. Pattwell, Eric C. Holland
2017-07-31

With an unsurpassed capacity for invasion into normal brain tissue, glioblastoma multiforme is the most lethal primary brain tumor. New research suggests that altering a subset of extracellular matrix factors, including interferon regulatory factor (IRF)3 and casein kinase (CK)2, may decrease the migratory potential of these aggressive tumors.

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