Category: Stem Cells

Blood Stem Cells Grown in the Lab

Two teams of scientists have generated blood stem cells by reprogramming either human or mouse cells. In both cases, these hematopoietic stem cells successfully produced blood cells when implanted into mice. “This is important...

CHILD ARCHIVE CHILD ARCHIVE
CHILD ARCHIVE CHILD ARCHIVE

iPS cell therapy reported safe

Japanese researchers reported this week that the first trial of induced pluripotent stem (iPS) cells in a human has proved safe and effective in halting the progression of age-related macular degeneration (AMD), though there...

CHILD ARCHIVE CHILD ARCHIVE
CHILD ARCHIVE CHILD ARCHIVE
CHILD ARCHIVE

From Stem Cell to Oocyte In a Dish

Scientists have for this first time reprogrammed murine embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into fully functional oocytes in the laboratory. The paper describing the technique, published today (October 17)...

CHILD ARCHIVE

Donor Stem Cells Improve Cardiac Function

Cardiac muscle cells derived from induced pluripotent stem cells (iPSCs) and injected into monkeys helped the animals’ hearts recover from a heart attack, according to a study published yesterday (October 10) inNature. The iPSCs...

CHILD ARCHIVE CHILD ARCHIVE
CHILD ARCHIVE CHILD ARCHIVE
CHILD ARCHIVE CHILD ARCHIVE
CHILD ARCHIVE

Translating stem cell quiescence

Many tissues harbor a reservoir of stem cells that remains quiescent but can be activated as needed for growth and repair. How cells enter, maintain, and then exit quiescence is incompletely defined. Studying skeletal...

CHILD ARCHIVE
CHILD ARCHIVE

CRISPR Corrects Retinal Disease Mutation

Retinitis pigmentosa, an inherited disease causing progressive degeneration of the retina, is repsonsible for blindness in approximately 1.5 million people worldwide. Using patient-derived stem cells, researchers in the U.S. have now used the CRISPR/Cas9...

CHILD ARCHIVE
CHILD ARCHIVE

STEM CELLS AND HEALTHY AGING

Research into stem cells and aging aims to understand how stem cells maintain tissue health, what mechanisms ultimately lead to decline in stem cell function with age, and how the regenerative capacity of somatic...

CHILD ARCHIVE

Stem Cell Similarities

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), reprogrammed from adult differentiated cells, reportedly behaved differently from one another in myriad studies. But these functional differences between cell types may not be...

CHILD ARCHIVE

Factor adjusts cell number in gut

Cells read their environment to trigger an appropriate response for tissue homeostasis. Work now shows that intestinal progenitor cells use the RNA-binding protein Lin-28 to detect such a change and trigger insulin signaling as...

CHILD ARCHIVE
CHILD ARCHIVE