Category: New therapy

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Rethinking a Cancer Drug Target

A protein thought to be essential for cancer cells may not be so essential after all, according to a study published today (March 24) in eLife. Researchers at Cold Spring Harbor Laboratory (CSHL) in...

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Notch1 promotes cancer spread

Mutations that activate Notch have been identified in several cancers. Weiland et al. find that Notch1 signaling within endothelial cells (ECs) promotes the invasion of distant organs by tumors. Abnormally high levels of active...

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Developing an HIV vaccine

In 2015, 17 million HIV-infected individuals worldwide were on antiretroviral drug therapies, which are remarkably effective in suppressing the virus. Yet, 6000 people a day became newly infected, making the quest for an effective...

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iPS cell therapy reported safe

Japanese researchers reported this week that the first trial of induced pluripotent stem (iPS) cells in a human has proved safe and effective in halting the progression of age-related macular degeneration (AMD), though there...

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Exploiting cancer metabolism

Cancer-specific cell surface proteins can be targeted for the delivery of therapeutic agents. However, specific proteins may not always be expressed by a tumor. Wang et al. overcome this challenge by designing sugars to...

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