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LAMP shines a light on Zika virus

Rapid and simple assays to detect infectious agents are key to tracking emerging epidemics. Chotiwan et al. describe a loop-mediated amplification (LAMP) assay that detects Zika virus RNA in human biofluids such as serum...

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Cellular Cartography

Over the next decade, researchers will compile a comprehensive and freely available map of the cells of the human body, complete with descriptions about their anatomy and function, according to a global initiative launched...

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From Stem Cell to Oocyte In a Dish

Scientists have for this first time reprogrammed murine embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into fully functional oocytes in the laboratory. The paper describing the technique, published today (October 17)...

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Building the route to metastasis

Dying tumor cells release the phospholipid S1P, which stimulates proinflammatory responses in tumor-associated macrophages, including secretion of the protein lipocalin-2. Jung et al.discovered that in the context of breast cancer, this pathway causes lymphatic...

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Circulating Tumor Cells Traverse Tiny Vasculature

Clusters of circulating tumor cells (CTCs) may play a larger role in cancer metastasis than previously thought. Researchers at Massachusetts General Hospital have now shown that these clusters can squeeze through microfluidic channels just...

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Facilitating Tumor Cell Migration

Emerging evidence suggests that metastasis the spread of cancer from one organ or tissue to another—is aided by a significant remodeling of the cancer cells’ surroundings. Now, researchers at MIT have made progress toward...

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