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  • Juno Halts Development of CAR T-Cell Cancer Immunotherapy Candidate JCAR015

    Juno Therapeutics has halted development of JCAR015, its lead chimeric antigen receptor (CAR) T-cell cancer immunotherapy indicated for adults with relapsed/refractory B-cell acute lymphoblastic leukemia (ALL), nearly 4 months after placing a Phase II...

    Cancer / Immunology / New therapy

  • Watch Full Movie Rings (2017)

    Rings (2017) Full Movie Online Watch Free , English Subtitles Full HD, Free Movies Streaming , Free Latest Films. Quality : HD Title : Rings. Director : F. Javier Gutiérrez Release : February 01,...

    Cancer / Immunology / New therapy

  • Exploring the Mechanisms of Music Therapy

    A man with Parkinson’s disease sitting in a crowded restaurant has to use the rest room, but he cannot get there. His feet are frozen; he cannot move. The more he tries, the more...

    New therapy / Techniques

  • Kite’s CAR T-Cell Therapy Success

    Six months after receiving infusions of their own T cells—genetically engineered ex vivo to carry chimeric antigen receptors (CAR) that bind to proteins on the surface of tumor cells—more than one-third of patients with...

    Cancer / New therapy

  • Canine Models for Alzheimer’s

    It’s no secret that fewer than 10 percent of investigational drugs achieve regulatory approval and reach the marketplace. But the chances of success for drugs developed to treat Alzheimer’s disease are even more grim....

    Neuroscience / Techniques

  • An epigenetics gold rush: new controls for gene expression

    Some big ideas seem to appear out of nowhere, but in 2008 Chuan He deliberately went looking for one. The US National Institutes of Health had just launched grants to support high-risk, high-impact projects,...

    Genetics

  • Itch Neurons in Mouse Spinal Cords Can Sense Pain

    Neuroscientists have long debated how itch and pain overlap in the nervous system. Although itch was once thought to arise from the same neurons that generate pain, later observations disputing this theory led many...

    Neuroscience

  • Antibiotic tolerance facilitates the evolution of resistance

    Resistance on a background of tolerance Bacteria survive antibiotic exposure either because they are quiescent when antibiotics are around in the highest concentrations (i.e., tolerance) or because they acquire active biochemical resistance mechanisms (i.e.,...

    Biochemistry

  • Why tolerance invites resistance

    Bacteria use two strategies to avoid being killed by antibiotics: resistance and tolerance. Resistance mechanisms such as destruction of a drug or modification of its target allow bacteria to grow in the presence of...

    Biochemistry

  • How red berries reduce inflammation

    Members of the interleukin-17 (IL-17) family of proinflammatory cytokines are important in the immune response to infections. However, too much IL-17 signaling is associated with autoimmune inflammatory diseases, such as asthma, psoriasis, and rheumatoid...

    Immunology